Gene information
Official symbol DRD1
Official full name dopamine receptor D1
Gene type protein-coding gene
Chromosome5q35.2
Gene familyDopamine receptors
Resources
Entrez Gene 1812
HGNC HGNC:3020
Ensembl ENSG00000184845
Vega OTTHUMG00000130557
UCSC uc003mcz.4
GO terms: 131 records
GO Description Category LogP Number of genes Detail
GO:0001505 regulation of neurotransmitter levels GO Biological Processes -3.63969141 10 More
GO:0001659 temperature homeostasis GO Biological Processes -5.81640478 6 More
GO:0001764 neuron migration GO Biological Processes -3.12579181 7 More
GO:0003012 muscle system process GO Biological Processes -27.3938503 63 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003018 vascular process in circulatory system GO Biological Processes -47.1670528 52 More
GO:0006468 protein phosphorylation GO Biological Processes -5.36604576 56 More
GO:0006576 cellular biogenic amine metabolic process GO Biological Processes -2.33647794 5 More
GO:0006584 catecholamine metabolic process GO Biological Processes -3.22341771 8 More
GO:0006606 protein import into nucleus GO Biological Processes -2.02717768 5 More
GO:0006913 nucleocytoplasmic transport GO Biological Processes -1.63729080 7 More
GO:0006939 smooth muscle contraction GO Biological Processes -6.47455620 13 More
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO Biological Processes -7.01019683 9 More
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO Biological Processes -9.16710904 33 More
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO Biological Processes -6.95524830 22 More
GO:0007190 activation of adenylate cyclase activity GO Biological Processes -5.90548425 6 More
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway GO Biological Processes -11.6592522 24 More
GO:0007204 positive regulation of cytosolic calcium ion concentration GO Biological Processes -15.6883547 39 More
GO:0007268 chemical synaptic transmission GO Biological Processes -4.44678751 35 More
GO:0007420 brain development GO Biological Processes -11.5572036 75 More
GO:0007610 behavior GO Biological Processes -18.1916656 76 More
GO:0007611 learning or memory GO Biological Processes -7.55755517 33 More
GO:0007612 learning GO Biological Processes -4.32260958 18 More
GO:0007613 memory GO Biological Processes -4.31484432 16 More
GO:0007626 locomotory behavior GO Biological Processes -5.45844211 23 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008306 associative learning GO Biological Processes -3.80327331 12 More
GO:0008643 carbohydrate transport GO Biological Processes -1.80096590 4 More
GO:0009308 amine metabolic process GO Biological Processes -2.23849437 5 More
GO:0009410 response to xenobiotic stimulus GO Biological Processes -32.6021211 82 More
GO:0009712 catechol-containing compound metabolic process GO Biological Processes -3.22341771 8 More
GO:0010001 glial cell differentiation GO Biological Processes -13.0211768 33 More
GO:0010959 regulation of metal ion transport GO Biological Processes -23.6318171 71 More
GO:0014075 response to amine GO Biological Processes -4.21089449 9 More
GO:0015850 organic hydroxy compound transport GO Biological Processes -17.9399475 23 More
GO:0017157 regulation of exocytosis GO Biological Processes -7.48561663 15 More
GO:0018958 phenol-containing compound metabolic process GO Biological Processes -4.03177682 7 More
GO:0021537 telencephalon development GO Biological Processes -6.21909725 29 More
GO:0021543 pallium development GO Biological Processes -4.55337429 20 More
GO:0021782 glial cell development GO Biological Processes -9.97103962 23 More
GO:0021885 forebrain cell migration GO Biological Processes -5.92071483 13 More
GO:0021953 central nervous system neuron differentiation GO Biological Processes -5.15897962 21 More
GO:0021954 central nervous system neuron development GO Biological Processes -2.16280095 9 More
GO:0022029 telencephalon cell migration GO Biological Processes -5.36863544 12 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030425 dendrite GO Cellular Components -4.55233052 48 More
GO:0030534 adult behavior GO Biological Processes -6.59104580 21 More
GO:0030594 neurotransmitter receptor activity GO Molecular Functions -2.67300750 6 More
GO:0030900 forebrain development GO Biological Processes -11.1545964 48 More
GO:0031253 cell projection membrane GO Cellular Components -3.08510132 12 More
GO:0031279 regulation of cyclase activity GO Biological Processes -6.38196333 9 More
GO:0031281 positive regulation of cyclase activity GO Biological Processes -5.63918224 7 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0033238 regulation of cellular amine metabolic process GO Biological Processes -3.34516618 7 More
GO:0033555 multicellular organismal response to stress GO Biological Processes -7.79385832 16 More
GO:0034330 cell junction organization GO Biological Processes -7.96624809 49 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034764 positive regulation of transmembrane transport GO Biological Processes -18.2616571 46 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0034767 positive regulation of ion transmembrane transport GO Biological Processes -11.2867591 18 More
GO:0035150 regulation of tube size GO Biological Processes -44.5138102 41 More
GO:0035296 regulation of tube diameter GO Biological Processes -44.6572858 41 More
GO:0035637 multicellular organismal signaling GO Biological Processes -4.89020616 9 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042063 gliogenesis GO Biological Processes -20.3412228 47 More
GO:0042311 vasodilation GO Biological Processes -18.7593927 16 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0042417 dopamine metabolic process GO Biological Processes -2.27643592 3 More
GO:0042596 fear response GO Biological Processes -3.60825621 7 More
GO:0043266 regulation of potassium ion transport GO Biological Processes -7.37974754 20 More
GO:0043268 positive regulation of potassium ion transport GO Biological Processes -3.46605627 5 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043270 positive regulation of ion transport GO Biological Processes -23.5832054 34 More
GO:0043279 response to alkaloid GO Biological Processes -4.89883771 15 More
GO:0045211 postsynaptic membrane GO Cellular Components -5.83105498 30 More
GO:0045761 regulation of adenylate cyclase activity GO Biological Processes -6.38434532 8 More
GO:0045762 positive regulation of adenylate cyclase activity GO Biological Processes -5.34310134 6 More
GO:0046928 regulation of neurotransmitter secretion GO Biological Processes -1.71479923 4 More
GO:0048167 regulation of synaptic plasticity GO Biological Processes -4.27696718 22 More
GO:0048871 multicellular organismal homeostasis GO Biological Processes -14.5562171 53 More
GO:0050804 modulation of chemical synaptic transmission GO Biological Processes -15.2260557 60 More
GO:0050805 negative regulation of synaptic transmission GO Biological Processes -5.05172294 12 More
GO:0050806 positive regulation of synaptic transmission GO Biological Processes -4.32260958 18 More
GO:0050808 synapse organization GO Biological Processes -6.17744712 32 More
GO:0050890 cognition GO Biological Processes -8.00500082 37 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051169 nuclear transport GO Biological Processes -1.63729080 7 More
GO:0051170 import into nucleus GO Biological Processes -1.96322846 5 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051279 regulation of release of sequestered calcium ion into cytosol GO Biological Processes -5.25087734 14 More
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol GO Biological Processes -3.97244449 5 More
GO:0051282 regulation of sequestering of calcium ion GO Biological Processes -7.93009971 22 More
GO:0051339 regulation of lyase activity GO Biological Processes -7.52607558 10 More
GO:0051349 positive regulation of lyase activity GO Biological Processes -6.76353457 8 More
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway GO Biological Processes -4.39154198 8 More
GO:0051588 regulation of neurotransmitter transport GO Biological Processes -2.92721908 6 More
GO:0051924 regulation of calcium ion transport GO Biological Processes -18.2498286 49 More
GO:0051952 regulation of amine transport GO Biological Processes -10.5179624 22 More
GO:0060322 head development GO Biological Processes -11.995356 79 More
GO:0060627 regulation of vesicle-mediated transport GO Biological Processes -25.1756709 46 More
GO:0071407 cellular response to organic cyclic compound GO Biological Processes -19.6857751 39 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0071867 response to monoamine GO Biological Processes -2.16454701 5 More
GO:0071868 cellular response to monoamine stimulus GO Biological Processes -2.21965331 5 More
GO:0071869 response to catecholamine GO Biological Processes -2.16454701 5 More
GO:0071870 cellular response to catecholamine stimulus GO Biological Processes -2.21965331 5 More
GO:0071875 adrenergic receptor signaling pathway GO Biological Processes -8.98205881 11 More
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway GO Biological Processes -9.78130162 11 More
GO:0090066 regulation of anatomical structure size GO Biological Processes -32.7608623 52 More
GO:0097447 dendritic tree GO Cellular Components -4.82959150 49 More
GO:0097746 blood vessel diameter maintenance GO Biological Processes -44.6572858 41 More
GO:0098793 presynapse GO Cellular Components -4.56552653 42 More
GO:0098794 postsynapse GO Cellular Components -5.82876983 23 More
GO:0098889 intrinsic component of presynaptic membrane GO Cellular Components -4.93822812 13 More
GO:0098916 anterograde trans-synaptic signaling GO Biological Processes -4.44678751 35 More
GO:0098960 postsynaptic neurotransmitter receptor activity GO Molecular Functions -2.86473787 9 More
GO:0098978 glutamatergic synapse GO Cellular Components -4.83590061 31 More
GO:0099056 integral component of presynaptic membrane GO Cellular Components -4.69230219 12 More
GO:0099177 regulation of trans-synaptic signaling GO Biological Processes -15.1793607 60 More
GO:0099536 synaptic signaling GO Biological Processes -6.00976162 42 More
GO:0099537 trans-synaptic signaling GO Biological Processes -5.17038357 38 More
GO:1901615 organic hydroxy compound metabolic process GO Biological Processes -22.7091625 41 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1903169 regulation of calcium ion transmembrane transport GO Biological Processes -8.80532519 28 More
GO:1903305 regulation of regulated secretory pathway GO Biological Processes -6.01402466 11 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:1904064 positive regulation of cation transmembrane transport GO Biological Processes -10.8655330 17 More
GO:1904427 positive regulation of calcium ion transmembrane transport GO Biological Processes -4.11465146 13 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000300 regulation of synaptic vesicle exocytosis GO Biological Processes -2.35732458 4 More
KEGG pathways: 6 records
KEGG Description Category LogP Number of genes Detail
hsa04020 Calcium signaling pathway KEGG Pathway -10.4415222 36 More
hsa04024 cAMP signaling pathway KEGG Pathway -7.78464854 30 More
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa04728 Dopaminergic synapse KEGG Pathway -2.98664168 7 More
hsa05030 Cocaine addiction KEGG Pathway -1.78827574 6 More
hsa05032 Morphine addiction KEGG Pathway -3.96184640 13 More
Drug-Gene interaction
view
Related drugs: 156 records
Drug name Interaction type Source PMID View
(r,s)-indatraline DTC view
acetophenazine antagonist TdgClinicalTrialTEND 1713928417016423 view
amitriptyline DTC view
amoxapine antagonist DTCChemblInteractions 11180191 view
amperozide DTC view
amsacrine DTC view
apocideine DTC view
apomorphine agonist TEND 1503766518691132124530491064198811752352 view
asenapine antagonist TdgClinicalTrial 1830881421655346 view
bay-11-7085 DTC view
benzamil DTC view
benzoxathian DTC view
bp-897 DTC view
bromocriptine agonist DTC 18691132 view
bupropion PharmGKB view
butaclamol DTC view
calcimycin DTC view
capsazepine DTC view
carphenazine antagonist TdgClinicalTrialTEND 488739348890584861216 view
carvedilol DTC view
cgs-15943 DTC view
cgs-21680 DTC view
chembl111545 DTC view
chembl123349 DTC view
chembl1256697 DTC view
chembl1368696 DTC view
chembl22778 DTC view
chembl25554 DTC view
chembl284609 DTC view
chembl291143 DTC view
chembl305195 DTC view
chembl322970 DTC view
chembl336208 DTC view
chembl35354 DTC view
chembl403183 DTC view
chembl429095 DTC view
chembl445102 DTC view
chembl601364 DTC view
chembl605003 DTC view
chembl63329 DTC view
chembl86931 DTC view
chlorprothixene antagonist TdgClinicalTrialTEND 18305651713928417016423 view
clomipramine DTC view
clorotepine DTC view
clozapine antagonist DTCTdgClinicalTrialTENDPharmGKB 1709296911752352 view
cocaine TEND view
cyclic adenosine monophosphate DTC view
cyclobenzaprine DTC view
cyproheptadine DTC view
deoxiepinephrine DTC view
dextroamphetamine PharmGKB 23952191 view
dicyclomine DTC view
dihydrexidine DTCTTD 1598561219744859 view
dihydroergocristine agonistantagonist DTC 1492857 view
dihydroergotamine DTC view
dipyridamole DTC view
dobutamine DTC view
dopamine agonist DTC 174681751730141017449449174552121069170017394052 view
e-doxepin DTC view
e-flupentixol TdgClinicalTrialTEND view
ecopipam antagonist TdgClinicalTrialTTD view
efaroxan DTC view
elliptecine DTC view
enoximone DTC view
epinastine DTC view
epinephrine DTC view
ergoloid mesylates agonist ChemblInteractions view
etilevodopa TdgClinicalTrial view
fenoldopam agonist DTCTdgClinicalTrialTENDTTD 81035961929372811752352 view
fenoldopam mesylate agonist ChemblInteractions view
fluoxetine DTC view
flupentixol antagonist DTC 10531405171111721713928417016423 view
fluphenazine antagonist DTCTdgClinicalTrialTEND 11113312118737061053140511752352 view
gossypol DTC view
gr-127935 DTC view
gw7647 DTC view
haloperidol antagonist DTCPharmGKB 270234371053140511752352 view
idarubicin DTC view
ifenprodil DTC view
iloperidone antagonist TdgClinicalTrial 23272794 view
imipramine binder DTC 9686407 view
ketanserin antagonist DTC view
ketotifen DTC view
levodopa agonist DTCTdgClinicalTrialTEND 11978145185493479633680 view
lisuride agonistantagonist TdgClinicalTrialTEND 186911321713928417016423 view
lithium PharmGKB 21047205 view
loxapine binderantagonist DTCTEND 11752352 view
maprotiline DTC view
melevodopa TdgClinicalTrial view
metergoline DTC view
methylergonovine antagonist DTCTdgClinicalTrialTENDTTD 1593049910200235117523521713928417016423 view
methylergonovine maleate antagonist ChemblInteractions view
methylphenidate PharmGKB 23952191 view
methysergide DTC view
metitepine DTC view
metizoline DTC view
mianserin binder DTC view
mifepristone DTC view
minaprine agonist TdgClinicalTrialTEND 78628621713928417016423 view
molindone DTC view
n-desmethylclozapine DTC view
nan-190 DTC view
nicardipine DTC view
nicotine PharmGKB 18092181 view
nifedipine DTC view
nipecotic acid DTC view
norepinephrine DTC view
nortriptyline DTC view
olanzapine antagonist TdgClinicalTrialTEND 183088141784891915771415117523522503203010227113 view
oleoyl dopamine DTC view
opipramol DTC view
paliperidone antagonist DTC 75209087531353 view
palmitoyl-carnitine DTC view
pergolide agonist DTCTdgClinicalTrialTENDTTD 186911321064198811752352 view
pergolide mesylate agonist ChemblInteractions view
perphenazine antagonist DTCTdgClinicalTrialTEND 257310417455212 view
phenamil DTC view
phenylephrine DTC view
phenyltoloxamine TTD view
piceatannol DTC view
pimozide antagonist ChemblInteractions view
pirenperone DTC view
pirenzepine DTC view
preclamol DTC view
prochlorperazine antagonist TEND view
promazine antagonist DTCTdgClinicalTrialTEND 1713928417016423 view
promethazine DTC view
propafenone DTC view
propiomazine antagonist TdgClinicalTrialTEND 1713928417016423 view
protriptyline DTC view
quercetin DTC view
quetiapine antagonist TEND 220374071784891915337652 view
quinacrine DTC view
r-n-propylnorapomorphine DTC view
racepinephrine DTC view
rotigotine agonist TEND 18691132 view
sb-216763 DTC view
sb-242084 DTC view
semaxanib DTC view
sertraline DTC view
skf-38393 agonist DTC view
spermine DTC view
spiperone antagonist DTC view
stepholidine DTC 19744859 view
thiethylperazine antagonist TdgClinicalTrialTEND 1713928417016423 view
thioridazine antagonist DTCTdgClinicalTrialTEND 8720030 view
trazodone DTC view
trifluoperazine DTC view
triflupromazine antagonist DTCTdgClinicalTrialTEND 2391693013778817139284908156317016423 view
trimipramine binder DTC 8863001 view
tyramine DTC view
vinpocetine DTC view
yohimbine DTC view
zicronapine TTD view
zimeldine DTC view
zuclopenthixol antagonist TdgClinicalTrialTEND 102224411822319 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_000794.5:c.-48A>G genomics myocardial infarction[diagnosis] myocardial infarction Zhao Z et al. DNA Cell Biol. 2012
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